Bruch’s membrane is a highly specialized and multi-laminar structure in our retinas that forms the basis for mediating interactions between the retinal pigment epithelium and blood flow from the choroid. I’ve not seen many good images online, so figured this image from mouse would be a good addition showing the relationship of the basal surface of the RPE with Bruch’s membrane.
The annotated image shows Bruch’s membrane (B), the retinal pigment epithelium (RPE), a pigment granule (PG), the basal surface (BS) and choriocapillaris (CC).
Here, we have a slightly zoomed in image showing more detail of the relationship between the basal surface of the RPE and Bruch’s membrane.