Building Retinal Connectomes

This paper in the Current Opinion in Neurobiology outlines the fundamental approach for the creation of retinal connectomes and justifies why they need to be constructed at nominally 2nm resolution with complete annotation of connectivity with molecular tags defining class membership of cells in the connectome volume.  Completeness of any connectome requires extensive descriptions of all participating objects in the volume to complete an adjacency matrix of that neural system.

Notably, this approach is also extensible to any connectome project.  Authors were Robert E. Marc, myself, J. Scott Lauritzen, Carl B. Watt and James R. Anderson.

 

 

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