Optic Nerve Head Drusen

Drusen in the retina is a common finding in aging retina, forming deposits in the retina between Bruch’s membrane and the retinal pigment epithelium.  Most people over 40 start to accumulate some drusen, but increasing amounts of drusen formation can indicate pathological developments associated with age related macular degeneration, (AMD).  Cristine Curcio has been chasing …

Acute Zonal Occult Outer Reinopathy (AZOOR)

This photo shows peripheral vasculitis in a patient with Acute Zonal Occult Outer Retinopathy (AZOOR). Five images were taken in each eye and composited together to show the peripheral changes taking place in the mid arterivenous phase of the fluorescein angiogram. This image was made by James Gilman of the Moran Eye Center using a 102 degree non-contact …

Interesting Paper: Gene Regulator, Onecut1 Important To Retinal Development And Integrity

This paper, Onecut1 Is Essential for Horizontal Cell Genesis and Retinal Integrity in the Journal of Neuroscience by authors Fuguo Wu, Renzhong Li, Yumiko Umino, Tadeusz J. Kaczynski, Darshan Sapkota, Shengguo Li, Mengqing Xiang, Steven J. Fliesler, David M. Sherry, Maureen Gannon, Eduardo Solessio, and Xiuqian Mu describes the gene regulator Onecut1 as being the key to healthy retinal …