Notable Paper: Network Deficiency Exacerbates Impairment in a Mouse Model of Retinal Degeneration

This paper by Christopher W. Yee, Abduqodir H. Toychiev and Botir T. Sagdullaev examines the role that neural oscillations play in normal and pathological states.  In a neurodegenerative model of retinitis pigmentosa, the authors examined the activity of neural networks in the rd1 mouse model and compared that activity to the wild type.  The authors …

Giant Squid Eyes

A recent paper by Dan-Eric Nilsson, Eric J. Warrant, Sönke Johnsen, Roger Hanlon and Nadav Shashar reports on the eyes of some of the most mysterious of creatures, Architeuthis and Mesonychoteuthis, the giant and colossal deep sea squid respectively. We here at Webvision love all things retina and would deeply love to get our hands …

Great Review: Defective Trafficking of Rhodopsin and Its Role In Retinal Degenerations

This is a great review paper on the role of rhodopsin trafficking and its influence on retinal degenerative disease by TJ Hollingsworth and Alecia Gross.  Rhodopsin delocalization in rod photoreceptors has been recognized for some time as one of the first indications of retinal photoreceptor cell stress in retinal degenerative diseases, so I was intrigued …

Pseudoexfoliation

This image demonstrates pseudo-exfoliation syndrome of the lens capsule.   Photograph was made by James Gilman of the Moran Eye Center using broad tangential illumination with a Zeiss photo slitlamp and a Nikon D-1X camera.

Notable Paper: Gene Therapy Rescues Photoreceptor Blindness in Dogs and Paves The Way for Treating Human X-linked Retinitis Pigmentosa

This paper in PNAS by William A. Beltran, Artur V. Cideciyan, Alfred S. Lewin, Simone Iwabe, Hemant Khanna, Alexander Sumaroka, Vince A. Chiodo, Diego S. Fajardo, Alejandro J. Román, Wen-Tao Deng, Malgorzata Swider, Tomas S. Alemán, Sanford L. Boye, Sem Genini, Anand Swaroop, William W. Hauswirth, Samuel G. Jacobson and Gustavo D. Aguirre is a continuation …

Jumping Spiders Use Image Defocusing For Depth Perception

A study out in today’s Science Magazine by Takashi Nagata, Mitsumasa Koyanagi, Hisao Tsukamoto, Shinjiro Saeki, Kunio Isono, Yoshinori Shichida, Fumio Tokunaga, Michiyo Kinoshita, Kentaro Arikawa and Akihisa Terakita proposes that jumping spiders at least, use image defocusing to provide depth perception.  Jumping spiders (Salticidae) are the largest family of spiders and have perhaps the best visual …