Vogt Koyanagi Harada Syndrome (VKH)

This imagery is from a patient with Vogt Koyanagi Harada Syndrome (VKH).  VKH is a presumed autoimmune disease that presents with waxing and waning subretinal fluid.  There is chromic uveitis with other neurological and dermatological symptoms.  The precise mechanism of the disease is unknown, though it is thought that the autoimmune involvement of melanocytes in …

Activation of Survival Pathways In The Degenerating Retina of rd10 Mice

An interesting article was published  in Experimental Eye Research by Marijana Samardzija, Hedwig Wariwoda, Cornelia Imsand, Philipp Huber, Severin R. Heynen, Andrea Gubler and Christian Grimm that examines survival pathways that are induced in the retinas of rd10 mice.  Dynamics of retinal degeneration in the rd10 mouse was also examined including an analysis of retinal vasculature and …

Interesting Article: Cellular Resolution Panretinal Imaging of Optogenetic Probes Using a Simple Funduscope

An interesting paper by Adi Schejter, Limor Tsur, Nairouz Farah, Inna Reutsky-Gefen, Yishay Falick, and Shy Shoham published an interesting paper that shows in vivo fluorescent images with cellular resolution using optogenetic probes expressed in retinal ganglion cells by adapting a simple endoscope as a low cost fundoscopic imaging system. The authors were able to …