University of Utah              The JOHN A. MORAN EYE CENTER

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CYTOSOMICS, METABOLOMICS and COMPUTATIONAL MOLECULAR PHENOTYPING

Micromolecules: definitions & links	Cellular domains: Genome, preoteome & metabolome
Metabolic diversity: Scale, dynamics, & phyletics	Phenotyping strategies: proteomics vs metabolomics
CMP Platforms: Platforms and workflow overview	CMP Probes: The probe library
CMP Substrates: Molecular trapping & detection	CMP Datasets: Data arrays for multichannel imaging
CMP Analysis: pattern recognition theory and tools	CMP Exploration: N-space visualization tools
CMP Annotation: browsing & annotating data

CMP Platforms and Workflow

CMP is realized in three technical platforms. The ultrastructural platform delivers technologies for molecular trapping and fabrication of nano-scale section arrays. The hapten platform yields the library of IgG probes for quantitative micromolecular visualization. The computational platform allows the assembly of N-space datasets, classification via pattern recognition algorithms, N-space exploration tools, and cellular/signature annotation environments.

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