Interesting Review: Intrinsically Photosensitive Retinal Ganglion Cells

I remember when the first discussion of intrinsically photosensitive retinal ganglion cells (ipRGCs) started coming out.    My thinking at the time was: “Wow, cool concept… but how in the world could you stack enough opsins in two membranes to make for any psychophysical perception?”  In short, despite some years of predicting their presence, I did …

Interesting Paper: Gene Expression Changes Within Müller Glial Cells in Retinitis Pigmentosa

Retinal degenerations are accompanied by retinal remodeling events.  These events alter the structure and function of the retina and involve to a large extent, Müller cells which seem to serve as pathways for neuronal migration.  This paper by Karin Roesch, Michael B. Stadler and Constance L. Cepko looks at gene expression changes in the Müller cells, one …